Canine Hemophilia B

Canine Hemophilia B is a sex-linked bleeding disorder in canines caused by the absence of functional coagulation factor IX. It is an X-linked recessive disorder, which means that male dogs are either affected or clear of the disease. They cannot be an unaffected carrier. A female, on the other hand, can be affected, clear, or a carrier, but will show no, or far less severe involvement. Symptoms include bloody diarrhea, bleeding under the skin, lameness, respiratory difficulties due to bleeding into the chest and airways, paralysis, and even death due to bleeding into the brain and spinal cord. While gene transfer therapy has been proposed as a possibility for treatment of Hemophilia B, current treatment methods require the infusion of factor IX-rich plasma concentrates in response to bleeding.

Although distinct genetic mutations responsible for canine hemophilia B have been discovered for Airedales, Bull Terriers, Lhasa Apsos, Labrador Retrievers, German Wirehair Pointers, and mixed breeds, ongoing studies suggest that there may be more than one mutation responsible for hemophilia B within a given breed.

Volume discounts are available for Breeder Clubs, etc. Please contact us for more information.

Certification of Results

VetNostic Laboratories® will provide a certificate for each test result.

Samples

The following sample(s) can be submitted for the testing:
- Cheek swabs

Reporting Results

Test results can be viewed through your VetNostic Laboratories® web account within 10 business days from the moment the samples arrive at the laboratory. Results can also be reported via Mail, E-Mail, or Fax.

DNA Storage

VetNostic Laboratories provides DNA storage for all of our extracted specimens. If a customer wishes to perform an additional test on a previously extracted specimen they can simply call or email us with the animal's name and/or VNL number along with the test to be performed. This storage is provided free of charge.

Various Breeds



Price: $65.00
Number of dogs to be tested: Add To Cart