von Willebrand Disease - Type I

von Willebrand Disease (vWD) is the most commonly inherited bleeding disorder in dogs and has been reported in over 50 breeds, but it is most prevalent in the Corgi, Doberman Pinscher, German Shepherd Dog, German Shorthaired Pointer, Golden Retriever, Shetland Sheepdog and Standard Poodle. It is caused by a deficiency in the amount of a certain protein called von Willebrand factor, or vWF. vWF’s main function is to transport and bind coagulation factor VIII to injured blood vessels. The ‘type’ of vWD is partly determined by the amount of vWF in the blood. Type I is the most mild form and has been observed in the most breeds. Dogs with this type still produce vWF at varying degrees. Some possess enough that they may never be diagnosed, while others produce so little that they may suffer disproportionate bleeding following: injury, spaying/ neutering, ear cropping, tail docking. Type II is a very rare form found primarily in the German Shorthaired and German Wirehaired Pointers. Dogs with this type still produce vWF, but there are structural abnormalities that affect its function, and lead to more severe bleeding episodes. Type III is the most severe form of vWD, and is found primarily in the Shetland Sheepdog and Scottish Terrier. Dogs with this type produce virtually no vWF, and will usually have several bleeding episodes before reaching adulthood.

VetNostic Laboratories’ genetic tests for von Willebrand Disease can reliably identify dogs that are either clear, or possess one or two copies of the vWD causing gene. This clear, carrier, or affected result can help breeders determine which animals to include in their breeding program.

Volume discounts are available for Breeder Clubs, etc. Please contact us for more information.

Certification of Results

VetNostic Laboratories® will provide a certificate for each test result.


The following sample(s) can be submitted for the testing:
- Cheek swabs

Reporting Results

Test results can be viewed through your VetNostic Laboratories® web account within 10 business days from the moment the samples arrive at the laboratory. Results can also be reported via Mail, E-Mail, or Fax.

DNA Storage

VetNostic Laboratories provides DNA storage for all of our extracted specimens. If a customer wishes to perform an additional test on a previously extracted specimen they can simply call or email us with the animal's name and/or VNL number along with the test to be performed. This storage is provided free of charge.

Bernese Mountain Dog
Coton De Tulear
Doberman Pinscher
Drentse Patrijshond
German Pinscher
Kerry Blue Terrier
Manchester Terrier
Pembroke Welsh Corgi

Price: $65.00
Number of dogs to be tested: Add To Cart